Buy Phenibut HCl for Laboratory Research
Phenibut HCl (4-Amino-3-phenylbutanoic acid hydrochloride) is a synthetic β-Phenyl-GABA analogue widely used in laboratory investigations involving neurochemical signaling, GABA receptor pharmacology, and structure-activity relationship research. Researchers utilize Phenibut HCl as a reference compound for studying inhibitory neurotransmission and receptor-mediated molecular pathways under controlled experimental conditions.
Current scientific investigations continue evaluating Phenibut HCl in biochemical, cellular, and preclinical research models to better understand GABA-B receptor interactions and downstream signaling mechanisms. These studies are limited to laboratory environments and should not be interpreted as evidence of therapeutic efficacy or approved medical use.
Research Use Only. This product is intended exclusively for laboratory and scientific research and is not intended for human or veterinary use.
What Is Phenibut HCl?
Phenibut HCl is the hydrochloride salt of β-Phenyl-γ-Aminobutyric Acid (β-Phenyl-GABA), a synthetic analogue of gamma-aminobutyric acid (GABA). The addition of a phenyl group at the β-position distinguishes Phenibut from GABA and is associated with altered physicochemical and pharmacokinetic properties in laboratory investigations.
Originally synthesized in Russia during the 1960s, Phenibut has remained a subject of neurological and pharmacological research for decades. It is frequently used as a reference compound in studies examining GABA-related signaling pathways and receptor pharmacology.
Proposed Mechanism of Action
Preclinical studies indicate that Phenibut HCl primarily interacts with GABA-B receptors, making it useful for investigating inhibitory neurotransmission and receptor-mediated signaling under controlled laboratory conditions.
Researchers continue evaluating Phenibut HCl in studies involving:
- GABA-B receptor interaction
- Inhibitory neurotransmission research
- Neurochemical signaling pathways
- Receptor-ligand binding studies
- Structure-activity relationship (SAR) investigations
- Molecular pharmacology research
- Comparative studies with GABA analogues
Limited preclinical evidence has also explored possible indirect interactions involving voltage-gated calcium channel-related pathways and dopaminergic signaling systems. These observations remain investigational and require further scientific evaluation.
Chemical Properties of Phenibut HCl
| Chemical Name | 4-Amino-3-phenylbutanoic acid hydrochloride |
| Common Name | Phenibut HCl |
| Synonyms | β-Phenyl-GABA β-Phenyl-γ-Aminobutyric Acid Hydrochloride |
| CAS Number | 3060-41-1 |
| PubChem CID | 14113 |
| Molecular Formula | C10H14ClNO2 |
| Molecular Weight | 215.68 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% |
| Solubility | Freely soluble in water; slightly soluble in ethanol |
| Storage | Store at 2–8°C in a dry, airtight container protected from moisture. |
| Classification | Research Use Only (RUO) |
Possible Research Applications of Phenibut HCl
1. GABA-B Receptor Research
Phenibut HCl is frequently utilized to investigate GABA-B receptor activity, receptor pharmacology, and ligand-receptor interactions in experimental systems.
2. Neurochemical Signaling Studies
Researchers use Phenibut HCl to explore inhibitory neurotransmission and molecular pathways involved in neuronal communication.
3. Structure-Activity Relationship Research
Its unique β-phenyl substitution makes Phenibut HCl valuable for comparing structural modifications among GABA analogues and their receptor-binding characteristics.
4. Comparative Pharmacology
Phenibut HCl is commonly examined alongside other GABA-related compounds in studies investigating receptor selectivity and molecular signaling mechanisms.
Why Buy Phenibut HCl from PureRawz?
PureRawz supplies high-purity Phenibut HCl intended exclusively for laboratory research. Every batch undergoes rigorous analytical testing to verify identity, purity, and consistency before distribution.
Available quality documentation includes:
- Certificate of Analysis (COA)
- Third-party purity verification
- Identity confirmation
- Batch consistency testing
- Analytical quality control
Frequently Asked Questions
What is Phenibut HCl?
Phenibut HCl is the hydrochloride salt of β-Phenyl-GABA, a synthetic GABA analogue investigated in laboratory research involving inhibitory neurotransmission and GABA-B receptor pharmacology.
What is Phenibut HCl researched for?
Researchers investigate Phenibut HCl for GABA-B receptor activity, neurochemical signaling, receptor-ligand interactions, molecular pharmacology, and comparative studies involving GABA analogues.
How is Phenibut HCl quality verified?
Quality is verified through analytical testing, including identity verification, purity analysis, and batch-specific Certificates of Analysis (COAs).
Is Phenibut HCl intended for human consumption?
No. Phenibut HCl is supplied exclusively for laboratory research and analytical investigations. It is not intended for human or veterinary use.
Research Use Disclaimer
This information is provided solely for educational and scientific purposes and does not constitute medical advice.
Products sold by PureRawz are intended exclusively for laboratory research use. They are not FDA-approved drugs, dietary supplements, foods, cosmetics, or medical devices and are not intended for human or veterinary consumption.
All clinical research must be conducted under the oversight of the appropriate Institutional Review Board (IRB). All preclinical research involving animals must be be conducted under the oversight of the appropriate Institutional Animal Care and Use Committee (IACUC) in accordance with applicable regulations and the Animal Welfare Act (AWA).
Our content is intended for informational purposes only. By completing and paying for your order, you agree to our Terms and Conditions. Customer satisfaction is our priority. If you are not completely satisfied with your purchase, please contact support@purerawz.co.
ATTENTION: ALL PRODUCTS ARE FOR LABORATORY AND RESEARCH PURPOSES ONLY. NOT FOR HUMAN OR VETERINARY USE.
References
- Lapin I. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Reviews. 2001. PubMed
- Samokhvalov AV, Paton-Gay CL, Balchand K. Phenibut dependence. BMJ Case Reports. 2013. PubMed
- Ahuja T, et al. Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal. Case Reports in Psychiatry. 2018. PubMed
- Shulgina GI. On neurotransmitter mechanisms of reinforcement and internal inhibition. Pavlovian Journal of Biological Science. 1986.
- PubChem. Phenibut (CID 14113). National Center for Biotechnology Information. https://pubchem.ncbi.nlm.nih.gov/compound/14113
- Cayman Chemical. Phenibut Hydrochloride Analytical Reference Standard.
- Owen DR, et al. Safety and Tolerability of the Anxiolytic and Nootropic Drug Phenibut: A Systematic Review. PubMed
Related Research Compounds
Researchers studying Phenibut HCL may also explore related neurological research compounds, including
Phenibut FAA,
Noopept, and
Phenylpiracetam, which are investigated in controlled laboratory studies involving neurochemical signaling pathways.
Additional research compounds include
Piracetam,
Selank, and
Semax, commonly studied in experimental neuroscience and peptide research models.
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