Buy Andarine (S-4) for Laboratory Research
Andarine (S-4) is a synthetic nonsteroidal Selective Androgen Receptor Modulator (SARM) widely utilized in laboratory research involving androgen receptor biology, receptor selectivity, and intracellular signaling pathways. Researchers investigate Andarine as a reference compound to study receptor-ligand interactions, transcriptional regulation, and molecular pharmacology under controlled experimental conditions.
Current preclinical research continues evaluating Andarine (S-4) in biochemical and cellular models to better understand selective androgen receptor activation, intracellular signaling networks, and receptor-mediated gene expression. These investigations are limited to laboratory and analytical research settings.
Research Use Only. This product is intended exclusively for laboratory and scientific research and is not intended for human or veterinary use.
Overview of Andarine (S-4)
Andarine, commonly referred to as S-4, is a synthetic small-molecule compound belonging to the selective androgen receptor modulator (SARM) class. It has become an important investigational compound for researchers studying androgen receptor pharmacology, receptor selectivity, and molecular signaling pathways.
Laboratory investigations continue examining Andarine’s interactions with androgen receptors, intracellular signaling proteins, and transcriptional regulatory mechanisms in controlled experimental systems.
Proposed Mechanism of Action
Published laboratory research suggests that Andarine may bind selectively to the ligand-binding domain of the androgen receptor (AR), forming an androgen receptor-ligand complex that undergoes conformational changes within the receptor.
Researchers continue investigating how this receptor complex may translocate into the nucleus, interact with androgen response elements (AREs), and regulate transcriptional activity associated with androgen-responsive genes.
Experimental investigations continue evaluating pathways involving:
- Selective androgen receptor binding
- Ligand-receptor interaction kinetics
- Receptor conformational changes
- Androgen response element (ARE) signaling
- Gene expression regulation
- PI3K-AKT-mTOR pathway investigations
- Structure-activity relationship (SAR) studies
These mechanistic descriptions are based on controlled laboratory investigations and should not be interpreted as evidence of therapeutic efficacy or clinical benefit.
Chemical Properties of Andarine (S-4)
| Compound Name | Andarine (S-4) |
| PubChem CID | 9824562 |
| CAS Number | 401900-40-1 |
| Molecular Formula | C19H18F3N3O6 |
| Molecular Weight | 441.4 g/mol |
| IUPAC Name | (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide |
| Classification | Selective Androgen Receptor Modulator (SARM) |
| Purity | ≥98% (Batch Dependent) |
| Storage | Store according to laboratory recommendations in a cool, dry environment protected from moisture and light. |
Possible Research Applications of Andarine (S-4)
1. Androgen Receptor Biology
Researchers investigate Andarine to better understand androgen receptor binding, receptor selectivity, and ligand-receptor interaction kinetics in experimental systems.
2. Molecular Signaling Research
Laboratory studies examine receptor-mediated intracellular signaling pathways, including investigations involving PI3K-AKT-mTOR signaling and downstream molecular responses.
3. Gene Expression Studies
Experimental models utilize Andarine to investigate androgen-responsive transcriptional regulation and molecular signaling associated with receptor activation.
4. Structure-Activity Relationship (SAR) Research
Researchers continue evaluating how structural characteristics influence receptor affinity, selectivity, and signaling behavior in biochemical models.
5. Drug Discovery Research
Andarine serves as an investigational reference compound during early-stage research involving selective androgen receptor modulators and related molecular scaffolds.
Why Buy Andarine (S-4) from PureRawz?
Every batch of Andarine undergoes rigorous analytical testing to verify purity, identity, and batch consistency before distribution for laboratory research.
Quality documentation may include:
- Certificate of Analysis (COA)
- High-Performance Liquid Chromatography (HPLC)
- Mass Spectrometry (MS)
- Identity Verification
- Purity Analysis
- Batch Consistency Testing
PureRawz supplies high-quality research compounds manufactured according to strict laboratory quality standards.
Frequently Asked Questions
What is Andarine (S-4)?
Andarine (S-4) is a synthetic selective androgen receptor modulator (SARM) investigated in laboratory research involving receptor biology, molecular pharmacology, and intracellular signaling pathways.
What is Andarine researched for?
Researchers investigate Andarine to study androgen receptor interactions, ligand-receptor binding, transcriptional regulation, intracellular signaling pathways, and structure-activity relationships under controlled laboratory conditions.
How is Andarine quality verified?
Quality is typically verified through analytical methods including HPLC, mass spectrometry, identity testing, purity analysis, and batch-specific Certificates of Analysis.
Is Andarine intended for human consumption?
No. Andarine (S-4) is supplied exclusively for laboratory research purposes and is not intended for human or veterinary use.
Research Use Disclaimer
The information provided is intended solely for educational and scientific purposes and should not be interpreted as medical advice.
Products sold by PureRawz are intended exclusively for laboratory research use. They are not FDA-approved drugs, dietary supplements, foods, cosmetics, or medical devices and are not intended for human or veterinary consumption.
All research should be conducted in accordance with applicable institutional guidelines, including IRB or IACUC oversight where appropriate.
ATTENTION: ALL PRODUCTS ARE FOR LABORATORY RESEARCH PURPOSES ONLY. NOT FOR HUMAN OR VETERINARY USE.
References
- Gao W, Reiser PJ, Coss CC, et al. Selective Androgen Receptor Modulator Treatment Improves Muscle Strength and Body Composition and Prevents Bone Loss in Orchidectomized Rats. Endocrinology. 2005.
- Yavuz M, Demircan T. Exploring the Potentials of S4, a Selective Androgen Receptor Modulator, in Glioblastoma Multiforme Therapy. Toxicology and Applied Pharmacology. 2024.
- PubChem Compound Database. Andarine (S-4). CID: 9824562.
Related Research Compounds
Researchers studying Andarine (S-4) also explore
RAD-140,
Ostarine (MK-2866),
Ligandrol (LGD-4033), and
YK-11 for SARM research.
Additional SARM studies may include
RAD-150,
LGD-3303, and
S-23 in laboratory androgen receptor research.
Researchers may also compare
Piracetam,
Noopept, and
Phenylpiracetam in broader molecular research studies.
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